Thanks to the gathering of the community of Lyon and St Etienne, bringing together researchers, clinicians, students and companies, this first international conference will aim at exploring how and to what extent exercise can be beneficial for the main cells of the musculoskeletal system (muscle, tendon, bone, cartilage, vessel). This day will offer the opportunity to highlight both basic research carried out at a preclinical level and investigations conducted in healthy subjects or cohorts of patients. Cellular, molecular and functional approaches will be highlighted during this conference (flash presentations and paper posters).